Biohacking — also known as DIY biology — is an extremely broad and amorphous term that can cover a huge range of activities from performing science experiments on yeast or other organisms, to tracking your own sleep and diet, to changing your own biology by pumping a younger person’s blood into your veins in the hope that it’ll fight aging.

As biohacking starts to appear more often in headlines — and, recently, in a fascinating Netflix series called Unnatural Selection — it’s worth getting clear on some of the fundamentals. Here are nine questions that can help you make sense of biohacking.

1. First of all, what exactly is biohacking? What are some common examples of it?
2. Why are people doing this? What drives someone to biohack themselves?
3. How different is biohacking from traditional medicine? What makes something “count” as a biohacking pursuit?
4. So how much of this is backed by scientific research?
5. This all sounds like it can be taken to extremes. What are the most dangerous types of biohacking being tried?
6. Are all these biohacking pursuits legal?
7. One of the more ambitious types of biohacking is life extension, the attempt to live longer or even cheat death entirely. What are the physical limits of life extension?
8. Biohackers also include people who engage in DIY science without experimenting on themselves. What’s that form of biohacking like?
9. At its most extreme, biohacking can fundamentally alter human nature. Should we be worried?

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